Alon Diament

As a computational biologist and data scientist, I’m seeking to apply my knowledge in large-scale data analysis to the development of biomedical and biotechnological solutions.

I’m a 4th-year PhD candidate in the Computational Systems and Synthetic Biology Lab in Tel Aviv University under the supervision of Prof. Tamir Tuller. I’m an Azrieli fellow and a fellow of the Edmond J. Safra Center for Bioinformatics. Previously I studied at the Technion, where I completed M.Sc. in Electrical Engineering, and B.Sc. in Electrical Engineering and Physics.

• Modeling three-dimensional genomic organization in evolution and pathogenesis (2018)
  A Diament, T Tuller
  Seminars in Cell & Developmental Biology

• Tracking the evolution of 3D gene organization demonstrates its connection to phenotypic divergence (2017)
  A Diament, T Tuller
  Nucleic acids research 45 (8), 4330-4343

• Evidence of translation efficiency adaptation of the coding regions of the bacteriophage lambda (2017)
  E Goz, O Mioduser, A Diament, T Tuller

  DNA Research 24 (4), 333-342

• Estimation of ribosome profiling performance and reproducibility at various levels of resolution (2016)
  A Diament, T Tuller

  Biology direct 11 (1), 24

• Three-dimensional genomic organization of genes’ function in eukaryotes (2016)
  A Diament, T Tuller

  Evolutionary Biology, 233-252. website

• Rationally designed, heterologous S. cerevisiae transcripts expose novel expression determinants (2015)
  T Ben-Yehezkel, S Atar, H Zur, A Diament, E Goz, T Marx, R Cohen, …

  RNA biology 12 (9), 972-984

• Improving 3D genome reconstructions using orthologous and functional constraints (2015)
  A Diament, T Tuller

  PLoS computational biology 11 (5), e1004298

• Three-dimensional eukaryotic genomic organization is strongly correlated with codon usage expression and function (2014)
  A Diament, RY Pinter, T Tuller
  Nature communications 5, 5876

Here you will find some recent projects:

• Our method for inter-species comparison of 3D gene organization.
• A number of useful functions and models for gene sequence analysis, focusing on codon usage. These include, among others, the CUFS model that we developed to measure the distance between pairs of genes in terms of their codon usage.
• A toolbox for managing parallel jobs on a PBS cluster.

Here are a few links to some of the things I like:

• The Technicalities is our Indie-Yiddish duo, that even Lorde has heard of.
• My favorite childhood (and adulthood) toy.
• I opened a blog for the Tuller Lab students, where we share our tips and advice.
• I volunteer at MESILA, an aid and information center for refugees and migrant workers.

Feel free to contact me, I’d be happy to hear from you.

alon {at} alondmnt {dot} com